Congenital hypothyroidism, as studied in rats. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain.
To study the protective effects of maternal thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in congenital hypothyroidism, we gave pregnant rats methimazole (MMI), an antithyroid drug that crosses the placenta, and infused them with three different doses of T4 or T3. The concentrations of both T...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | angielski |
| Wydane: |
1990
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| Dostęp online: | https://doi.org/10.1172/jci114790 http://www.jci.org/articles/view/114790/files/pdf |
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