Detection of FLT3 Internal Tandem Duplication in Targeted, Short-Read-Length, Next-Generation Sequencing Data
A recurrent somatic mutation frequently found in cytogenetically normal acute myeloid leukemia (AML) is internal tandem duplication (ITD) in the fms-related tyrosine kinase 3 gene (FLT3). This mutation is generally detected in the clinical laboratory by PCR and electrophoresis-based product sizing....
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2012
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| 在线阅读: | https://doi.org/10.1016/j.jmoldx.2012.08.001 http://www.jmdjournal.org/article/S1525157812002590/pdf |
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