Detection of FLT3 Internal Tandem Duplication in Targeted, Short-Read-Length, Next-Generation Sequencing Data

Detection of FLT3 Internal Tandem Duplication in Targeted, Short-Read-Length, Next-Generation Sequencing Data

A recurrent somatic mutation frequently found in cytogenetically normal acute myeloid leukemia (AML) is internal tandem duplication (ITD) in the fms-related tyrosine kinase 3 gene (FLT3). This mutation is generally detected in the clinical laboratory by PCR and electrophoresis-based product sizing....

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Xehetasun bibliografikoak
Egile Nagusiak: David H. Spencer, Haley Abel, Christina M. Lockwood, Jacqueline E. Payton, Philippe Szankasi, Todd W. Kelley, Shashikant Kulkarni, John D. Pfeifer, Eric J. Duncavage
Formatua: Artigo
Hizkuntza:ingelesa
Argitaratua: 2012
Sarrera elektronikoa:https://doi.org/10.1016/j.jmoldx.2012.08.001
http://www.jmdjournal.org/article/S1525157812002590/pdf
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https://doi.org/10.1016/j.jmoldx.2012.08.001
http://www.jmdjournal.org/article/S1525157812002590/pdf

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