Tumor suppressor TSC1 is critical for T-cell anergy
T-cell anergy is a state of T cells that is hyporesponsive to stimulation via the T-cell receptor and costimulatory molecules and is thought to be important for self-tolerance. How T-cell anergy is regulated is still poorly understood. We report here that tuberous sclerosis (TSC)1 is critical for T-...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | English |
Published: |
2012
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Online Access: | https://doi.org/10.1073/pnas.1119744109 |
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