Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.

The prolactin (PRL) receptor is a member of the family of cytokine receptors that lack intrinsic tyrosine kinase activity but contain two conserved cysteines in their N-terminal regions and a WSXWS motif adjacent to their transmembrane domains. In a manner similar to the interferons (IFNs), exposure...

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Autores principales: Michael David, Emanuel F. Petricoin, Kazuhiko Igarashi, Gerald M. Feldman, D S Finbloom, A.C. Larner
Formato: Artigo
Lenguaje:inglés
Publicado: 1994
Acceso en línea:https://doi.org/10.1073/pnas.91.15.7174
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