Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.
The prolactin (PRL) receptor is a member of the family of cytokine receptors that lack intrinsic tyrosine kinase activity but contain two conserved cysteines in their N-terminal regions and a WSXWS motif adjacent to their transmembrane domains. In a manner similar to the interferons (IFNs), exposure...
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Autores principales: | , , , , , |
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Formato: | Artigo |
Lenguaje: | inglés |
Publicado: |
1994
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Acceso en línea: | https://doi.org/10.1073/pnas.91.15.7174 |
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