Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors

Abstract Background Assays of multiple tumor samples frequently reveal recurrent genomic aberrations, including point mutations and copy-number alterations, that affect individual genes. Analyses that extend beyond single genes are often restricted to examining pathways, interactions and functional...

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Bibliografische gegevens
Hoofdauteurs: Christopher A. Miller, Stephen H. Settle, Erik P. Sulman, Kenneth Aldape, Aleksandar Milosavljevic
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2011
Online toegang:https://doi.org/10.1186/1755-8794-4-34
https://bmcmedgenomics.biomedcentral.com/counter/pdf/10.1186/1755-8794-4-34
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