Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

The human MHC represents the strongest susceptibility locus for autoimmune diseases. However, the identification of the true predisposing gene(s) has been handicapped by the strong linkage disequilibrium across the region. Furthermore, most studies to date have been limited to the examination of a s...

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Autors principals: John D. Rioux, Philippe Goyette, Timothy J. Vyse, Lennart Hammarström, Michelle M. A. Fernando, Todd J. Green, Philip L. De Jager, Sylvain Foisy, Joanne Wang, Paul I. W. de Bakker, Stephen J Leslie, Gil McVean, Leonid Padyukov, Lars Alfredsson, Vito Annese, David A. Hafler, Qiang Pan‐Hammarström, Ritva Matell, Stephen Sawcer, Alastair Compston, Bruce Cree, Daniel B. Mirel, Mark J. Daly, Tim Behrens, Lars Klareskog, Peter K. Gregersen, Jorge R. Oksenberg, Stephen L. Hauser
Format: Artigo
Idioma:anglès
Publicat: 2009
Accés en línia:https://doi.org/10.1073/pnas.0909307106
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https://doi.org/10.1073/pnas.0909307106

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