Hierarchical order of phosphorylation events commits Cdc25A to Beta-TrCP-dependent degradation
We have recently demonstrated that regulation of Cdc25A protein abundance during S phase and in response to DNA damage is mediated by SCF(betaTrCP) activity. Based on sequence homology of known betaTrCP substrates, we found that Cdc25A contains a conserved motif (DSG), phosphorylation of which is re...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , |
---|---|
Fformat: | Artigo |
Iaith: | Saesneg |
Cyhoeddwyd: |
2004
|
Mynediad Ar-lein: | https://doi.org/10.4161/cc.3.4.770 https://www.tandfonline.com/doi/pdf/10.4161/cc.3.4.770?needAccess=true |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|