Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases

One general principle of gene regulation is that DNA-binding transcription factors modulate transcription by recruiting cofactors that modify histones and chromatin structure. A second implicit principle is that a particular cofactor is necessary at all the target genes where the cofactor is recruit...

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Main Authors: David C. Bedford, Lawryn H. Kasper, Tomofusa Fukuyama, Paul K. Brindle
Formato: Revisão
Idioma:Inglês
Publicado em: 2010
Acesso em linha:https://doi.org/10.4161/epi.5.1.10449
https://www.tandfonline.com/doi/pdf/10.4161/epi.5.1.10449?needAccess=true&role=button
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