Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation
Accumulating evidence points to inflammation as a promoter of carcinogenesis. MyD88 is an adaptor molecule in TLR and IL-1R signaling that was recently implicated in tumorigenesis through proinflammatory mechanisms. Here we have shown that MyD88 is also required in a cell-autonomous fashion for RAS-...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | engleski |
| Izdano: |
2010
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| Online pristup: | https://doi.org/10.1172/jci42771 http://www.jci.org/articles/view/42771/files/pdf |
| Oznake: |
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