Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria
IDE (insulin-degrading enzyme) is a widely expressed zinc-metallopeptidase that has been shown to regulate both cerebral amyloid β-peptide and plasma insulin levels in vivo. Genetic linkage and allelic association have been reported between the IDE gene locus and both late-onset Alzheimer's dis...
Kaydedildi:
Asıl Yazarlar: | , , , , , , |
---|---|
Materyal Türü: | Artigo |
Dil: | İngilizce |
Baskı/Yayın Bilgisi: |
2004
|
Online Erişim: | https://doi.org/10.1042/bj20041081 |
Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|