Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins
Mitochondrial injury, characterized by outer membrane permeabilization and consequent release of apoptogenic factors, is a key to apoptosis of mammalian cells. Bax and Bak, two multidomain Bcl-2 family proteins, provide a requisite gateway to mitochondrial injury. However it is unclear how Bax and B...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2007
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| On-line přístup: | https://doi.org/10.1073/pnas.0703976104 |
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