Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells
The anti-tumoral effects of cannabinoids have been described in different tumor systems, including pancreatic adenocarcinoma, but their mechanism of action remains unclear. We used cannabinoids specific for the CB1 (ACPA) and CB2 (GW) receptors and metabolomic analyses to unravel the potential pathw...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2013
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| Online Access: | https://doi.org/10.1038/cddis.2013.151 https://www.nature.com/articles/cddis2013151.pdf |
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