KAP1/TRIM28: An inhibitor of IRF5 function in inflammatory macrophages
IRF5 plays a key role in the induction of pro-inflammatory cytokines, contributing to the plasticity and polarisation of macrophages to an M1 phenotype and initiation of a potent T(H)1-T(H)17 response. To better understand the means of IRF5 transcriptional action, we conducted a screen for IRF5-inte...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | inglés |
| Publicado: |
2012
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| Acceso en línea: | https://doi.org/10.1016/j.imbio.2012.07.026 |
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