DAI (DLM-1/ZBP1) as a Genetic Adjuvant for DNA Vaccines That Promotes Effective Antitumor CTL Immunity
DNA vaccination is an attractive approach to induce antigen-specific cytotoxic CD8(+) T lymphocytes (CTLs), which can mediate protective antitumor immunity. The potency of DNA vaccines encoding weakly immunogenic tumor-associated antigens (TAAs) can be enhanced by codelivering gene-encoded adjuvants...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | angielski |
| Wydane: |
2010
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| Dostęp online: | https://doi.org/10.1038/mt.2010.268 https://www.cell.com/article/S1525001616304087/pdf |
| Etykiety: |
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