Lipin1 Is a Key Factor for the Maturation and Maintenance of Adipocytes in the Regulatory Network with CCAAT/Enhancer-binding Protein α and Peroxisome Proliferator-activated Receptor γ2
Lipin1 expression was induced at a late stage of differentiation of 3T3-L1 preadipocytes and maintained at high levels in mature adipocytes. Knockdown of expression of lipin1 by small interfering RNA in 3T3-L1 preadipocytes almost completely inhibited differentiation into adipocytes, whereas overexp...
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Glavni autori: | , , , , , , , |
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Format: | Artigo |
Jezik: | engleski |
Izdano: |
2008
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Online pristup: | https://doi.org/10.1074/jbc.m804007200 http://www.jbc.org/article/S0021925820633130/pdf |
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