Cilostazol Protects Against Brain White Matter Damage and Cognitive Impairment in a Rat Model of Chronic Cerebral Hypoperfusion

Background and Purpose— White matter lesions contribute to cognitive impairment in poststroke patients. The present study was designed to assess the neuroprotective mechanisms of cilostazol, a potent inhibitor of type III phosphodiesterase, through signaling pathways that lead to activation of trans...

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Auteurs principaux: Terubumi Watanabe, Ning Zhang, Meizi Liu, Ryota Tanaka, Yoshikuni Mizuno, Takao Urabe
Format: Artigo
Langue:anglais
Publié: 2006
Accès en ligne:https://doi.org/10.1161/01.str.0000221783.08037.a9
https://www.ahajournals.org/doi/pdf/10.1161/01.STR.0000221783.08037.a9
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