In vitro and in vivo evaluation of cubosomes containing 5-fluorouracil for liver targeting
The objective of this study was to prepare cubosomal nanoparticles containing a hydrophilic anticancer drug 5-fluorouracil (5-FU) for liver targeting. Cubosomal dispersions were prepared by disrupting a cubic gel phase of monoolein and water in the presence of Poloxamer 407 as a stabilizer. Cubosome...
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Главные авторы: | , , |
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Формат: | Artigo |
Язык: | английский |
Опубликовано: |
2014
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Online-ссылка: | https://doi.org/10.1016/j.apsb.2014.12.001 |
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