Antinociceptive Effect of Morphine, but not μ Opioid Receptor Number, Is Attenuated in the Spinal Cord of Diabetic Rats
The mechanisms of decreased analgesic potency of mu opioids in diabetic neuropathic pain are not fully known. The authors recently found that G protein activation stimulated by the mu opioid agonist is significantly reduced in the spinal cord dorsal horn in diabetes. In the current study, they deter...
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| Main Authors: | , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2003
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| 在线阅读: | https://doi.org/10.1097/00000542-200312000-00026 https://pubs.asahq.org/anesthesiology/article-pdf/99/6/1409/338190/0000542-200312000-00026.pdf |
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