Antinociceptive Effect of Morphine, but not μ Opioid Receptor Number, Is Attenuated in the Spinal Cord of Diabetic Rats

The mechanisms of decreased analgesic potency of mu opioids in diabetic neuropathic pain are not fully known. The authors recently found that G protein activation stimulated by the mu opioid agonist is significantly reduced in the spinal cord dorsal horn in diabetes. In the current study, they deter...

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Bibliografische gegevens
Hoofdauteurs: Shao-Rui Chen, Hui‐Lin Pan
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2003
Online toegang:https://doi.org/10.1097/00000542-200312000-00026
https://pubs.asahq.org/anesthesiology/article-pdf/99/6/1409/338190/0000542-200312000-00026.pdf
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