Inhibiting AKT Phosphorylation Employing Non-Cytotoxic Anthraquinones Ameliorates TH2 Mediated Allergic Airways Disease and Rhinovirus Exacerbation

Inhibiting AKT Phosphorylation Employing Non-Cytotoxic Anthraquinones Ameliorates TH2 Mediated Allergic Airways Disease and Rhinovirus Exacerbation

BackgroundSevere asthma is associated with T helper (TH) 2 and 17 cell activation, airway neutrophilia and phosphoinositide-3-kinase (PI3K) activation. Asthma exacerbations are commonly caused by rhinovirus (RV) and also associated with PI3K-driven inflammation. Anthraquinone derivatives have been s...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Caio César de Souza Alves, Adam Collison, Luke Hatchwell, Maximilian Plank, Matthew Morten, Paul S. Foster, Sebastian L. Johnston, Cristiane França da Costa, Mauro V. de Almeida, Henrique Couto Teixeira, Ana Paula Ferreira, Joërg Mattes
Формат: Artigo
Хэл сонгох:англи
Хэвлэсэн: 2013
Онлайн хандалт:https://doi.org/10.1371/journal.pone.0079565
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0079565&type=printable
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Интернэт

https://doi.org/10.1371/journal.pone.0079565
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0079565&type=printable

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