Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

Through alternative polyadenylation, human mRNAs acquire longer or shorter 3' untranslated regions, the latter typically associated with higher transcript stability and increased protein production. To understand the dynamics of polyadenylation site usage, we performed transcriptome-wide mappin...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Georges Martín, Andreas Gruber, Walter Keller, Mihaela Zavolan
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2012
Urunga tuihono:https://doi.org/10.1016/j.celrep.2012.05.003
https://www.cell.com/article/S2211124712001271/pdf
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