A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion

SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins mediate fusion by pulling biological membranes together via a zippering mechanism. Recent biophysical studies have shown that t- and v-SNAREs can assemble in multiple stages from the N-termini toward the C-termini...

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Auteurs principaux: Feng Li, Daniel Kümmel, Jeff Coleman, Karin M. Reinisch, James E. Rothman, Frédéric Pincet
Format: Artigo
Langue:anglais
Publié: 2014
Accès en ligne:https://doi.org/10.1021/ja410690m
https://pubs.acs.org/doi/pdf/10.1021/ja410690m
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