ERK-mediated phosphorylation of Thr735 in TNFα-converting enzyme and its potential role in TACE protein trafficking

Tumor necrosis factor alpha-converting enzyme (TACE/ADAM17) has been implicated in the inducible shedding of numerous cell surface proteins. In light of this, the regulation of TACE catalytic activation and protein maturation has recently received considerable interest in the context of extracellula...

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Autori principali: Surinder M. Soond, Bethany Everson, David W. H. Riches, Gillian Murphy
Natura: Artigo
Lingua:inglese
Pubblicazione: 2005
Accesso online:https://doi.org/10.1242/jcs.02357
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