Increased Burden of Cardiovascular Disease in Carriers of <i>APOL1</i> Genetic Variants

Rationale: Two distinct alleles in the gene encoding apolipoprotein L1 ( APOL1 ), a major component of high-density lipoprotein, confer protection against Trypanosoma brucei rhodesiense infection and also increase risk for chronic kidney disease. Approximately 14% of Americans with African ancestry...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kaoru Ito, Alexander G. Bick, Jason Flannick, David J. Friedman, Giulio Genovese, Michael Parfenov, Steven R. DePalma, Namrata Gupta, Stacey Gabriel, Herman A. Taylor, Ervin R. Fox, Christopher Newton‐Cheh, Sekar Kathiresan, Joel N. Hirschhorn, David Altshuler, Martin R. Pollak, James G. Wilson, Jonathan G. Seidman, Christine E. Seidman
स्वरूप: Artigo
भाषा:अंग्रेज़ी
प्रकाशित: 2013
ऑनलाइन पहुंच:https://doi.org/10.1161/circresaha.114.302347
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