Vascular Klotho Deficiency Potentiates the Development of Human Artery Calcification and Mediates Resistance to Fibroblast Growth Factor 23
Klotho is known to function as a cofactor for the phosphatonin, fibroblast growth factor (FGF)-23 at the kidney. FGF-23 levels rise in chronic kidney disease (CKD) despite progression of accelerated vascular calcification. There are currently conflicting data on whether FGF-23 may exhibit direct vas...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Engels |
| Gepubliceerd in: |
2012
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| Online toegang: | https://doi.org/10.1161/circulationaha.111.053405 https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.111.053405 |
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