Bach1, a heme‐dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure

Abstract The mammalian transcription factor Bach1 functions as a repressor of the enhancers of heme oxygenase‐1 (HO‐1) gene (Hmox‐1) by forming heterodimers with the small Maf proteins such as MafK. The transcription of Hmox‐1 is regulated by the substrate of HO‐1, heme. Heme induces expression of H...

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Auteurs principaux: Shusuke Hira, Takeshi Tomita, Toshitaka Matsui, Kazuhiko Igarashi, Masao Ikeda‐Saito
Format: Revisão
Langue:anglais
Publié: 2007
Accès en ligne:https://doi.org/10.1080/15216540701225941
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1080/15216540701225941
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