Hijacking the Chromatin Remodeling Machinery: Impact of<i>SWI/SNF</i>Perturbations in Cancer

Abstract There is increasing evidence that alterations in chromatin remodeling play a significant role in human disease. The SWI/SNF chromatin remodeling complex family mobilizes nucleosomes and functions as a master regulator of gene expression and chromatin dynamics whose functional specificity is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bernard E. Weissman, Karen E. Knudsen
Format: Revisão
Sprache:Englisch
Veröffentlicht: 2009
Online-Zugang:https://doi.org/10.1158/0008-5472.can-09-2166
https://aacrjournals.org/cancerres/article-pdf/69/21/8223/2617367/8223.pdf
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