B7 Expression on T Cells Down-Regulates Immune Responses through CTLA-4 Ligation via R-T Interactions
Abstract Although B7 on APCs has a well-recognized role in T cell costimulation, little is known about the functional significance of constitutive and activation-induced B7 expression that also occurs on T cells. To analyze the role of B7 on T cells, B7-1/B7-2-deficient mice (B7 double knockout) and...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | 英語 |
出版事項: |
2004
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オンライン・アクセス: | https://doi.org/10.4049/jimmunol.172.1.34 https://journals.aai.org/jimmunol/article-pdf/172/1/34/1177937/34.pdf |
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