Activation of NF-κB1 by OX40 Contributes to Antigen-Driven T Cell Expansion and Survival

The costimulatory molecule OX40 (CD134) is required in many instances for effective T cell-mediated immunity, controlling proliferation, and survival of T cells after encountering specific Ag. We previously found that the functional targets of OX40 are survivin and aurora B that regulate proliferati...

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Principais autores: Jianxun Song, Takanori So, Michael Croft
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Acesso em linha:https://doi.org/10.4049/jimmunol.180.11.7240
https://journals.aai.org/jimmunol/article-pdf/180/11/7240/1255215/zim01108007240.pdf
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