Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture
Efficient pre-replication complex (pre-RC) formation on chromatin templates is crucial for the maintenance of genome integrity. However, the regulation of chromatin dynamics during this process has remained elusive. We found that a conserved protein, GRWD1 (glutamate-rich WD40 repeat containing 1),...
שמור ב:
Main Authors: | , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | אנגלית |
יצא לאור: |
2015
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גישה מקוונת: | https://doi.org/10.1093/nar/gkv509 https://academic.oup.com/nar/article-pdf/43/12/5898/16659479/gkv509.pdf |
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