Enhancement of Muscle T Regulatory Cells and Improvement of Muscular Dystrophic Process in mdx Mice by Blockade of Extracellular ATP/P2X Axis

Enhancement of Muscle T Regulatory Cells and Improvement of Muscular Dystrophic Process in mdx Mice by Blockade of Extracellular ATP/P2X Axis

Infiltration of immune cells and chronic inflammation substantially affect skeletal and cardiac muscle degeneration in Duchenne muscular dystrophy. In the immune system, extracellular adenosine triphosphate (ATP) released by dying cells is sensed as a danger associated molecular pattern through P2 p...

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Hauptverfasser: Elisabetta Gazzerro, Sımona Baldassari, Stefania Assereto, Floriana Fruscione, Angela Pistorio, Chiara Panicucci, Stefano Volpi, Lisa Perruzza, Chiara Fiorillo, Carlo Minetti, Elisabetta Traggiai, Fabio Grassi, Claudio Bruno
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2015
Online-Zugang:https://doi.org/10.1016/j.ajpath.2015.08.010
http://ajp.amjpathol.org/article/S0002944015004988/pdf
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https://doi.org/10.1016/j.ajpath.2015.08.010
http://ajp.amjpathol.org/article/S0002944015004988/pdf

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