BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase
Significance Transcriptional regulation of the rDNA cluster is a tightly regulated process owing to the cellular demand for ribosomal subunits. Dysregulation of ribosomal biogenesis is associated with genomic instability and tumor progression. Nucleolar-remodeling complex (NoRC) has emerged as a key...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | англи |
| Хэвлэсэн: |
2015
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| Онлайн хандалт: | https://doi.org/10.1073/pnas.1424705112 https://www.pnas.org/content/pnas/112/27/8338.full.pdf |
| Шошгууд: |
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