Hyperproduction of Proinflammatory Cytokines by WSX-1-Deficient NKT Cells in Concanavalin A-Induced Hepatitis
Abstract Administration of Con A induces liver injury that is considered to be an experimental model for human autoimmune or viral hepatitis, where immunopathology plays roles mediated by activated lymphocytes, especially NK1.1+ CD3+ NKT cells, and inflammatory cytokines, including IFN-γ and IL-4. I...
Shranjeno v:
Main Authors: | , , , , , , , , |
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Format: | Artigo |
Jezik: | angleščina |
Izdano: |
2004
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Online dostop: | https://doi.org/10.4049/jimmunol.172.6.3590 |
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