Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels.
Human platelets were found by immunoblot analysis to express protein kinase C (PKC) isozymes alpha, beta, delta, and zeta, but not gamma, epsilon, or eta. Exposure of platelets to thrombin, in the presence of 1 mM calcium, induced increased membrane association of PKC-alpha, -beta, and -zeta, while...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
1992
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| On-line přístup: | https://doi.org/10.1016/s0021-9258(19)49576-8 |
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