Mechanism of complement inactivation by glycoprotein C of herpes simplex virus.

Glycoprotein C (gC) of both herpes simplex virus type 1 (HSV-1) and HSV-2 interacts with complement C3b and protects the virus from complement-mediated neutralization. To study the mechanism by which gC modulates complement activation, we expressed both gC-1 and gC-2 in a baculovirus expression syst...

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Hauptverfasser: Ioanna Kostavasili, Arvind Sahu, Harvey M. Friedman, Roselyn J. Eisenberg, Gary H. Cohen, John D. Lambris
Format: Artigo
Sprache:Englisch
Veröffentlicht: 1997
Online-Zugang:https://doi.org/10.4049/jimmunol.158.4.1763
https://journals.aai.org/jimmunol/article-pdf/158/4/1763/1076540/1763.pdf
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