Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

We have demonstrated that the angiotensin-converting enzyme (ACE) genotype is associated with Alzheimer's disease (AD) in the Japanese population (1Hu J. Miyatake F. Aizu Y. Nakagawa H. Nakamura S. Tamaoka A. Takahashi R. Urakami K. Shoji M. Neurosci. Lett. 1999; 277: 65-67Crossref PubMed Scopu...

Furkejuvvon:

Bibliográfalaš dieđut
Váldodahkkit:	Jianguo Hu, Akira Igarashi, Makiko Kamata, Hachiro Nakagawa
Materiálatiipa:	Artigo
Giella:	eaŋgalasgiella
Almmustuhtton:	2001
Liŋkkat:	https://doi.org/10.1074/jbc.m104068200 http://www.jbc.org/article/S0021925819402937/pdf
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!

Geahča maid

The N‐terminal active centre of human angiotensin‐converting enzyme degrades Alzheimer amyloid β‐peptide
Dahkki: Ryutaro Oba, et al.
Almmustuhtton: (2005)

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ(1–42)) to Aβ(1–40), and Its Inhibition Enhances Brain Aβ Deposition
Dahkki: Zou, Kun, et al.
Almmustuhtton: (2007)

Charge Dependent Retardation of Amyloid β Aggregation by Hydrophilic Proteins
Dahkki: Assarsson, Anna, et al.
Almmustuhtton: (2014)

Charge Dependent Retardation of Amyloid β Aggregation by Hydrophilic Proteins
Dahkki: Anna Assarsson, et al.
Almmustuhtton: (2014)

New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity
Dahkki: Yuji Yoshiike, et al.
Almmustuhtton: (2001)

Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ<sub>1–42</sub>) to Aβ<sub>1–40</sub>, and Its Inhibition Enhances Brain Aβ Deposition
Dahkki: Kun Zou, et al.
Almmustuhtton: (2007)

Preventing β-amyloid fibrillization and deposition: β-sheet breakers and pathological chaperone inhibitors
Dahkki: Wisniewski, Thomas, et al.
Almmustuhtton: (2008)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
Dahkki: Abelein, Axel, et al.
Almmustuhtton: (2015)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
Dahkki: Axel Abelein, et al.
Almmustuhtton: (2015)

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
Dahkki: Joshi, P, et al.
Almmustuhtton: (2014)

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
Dahkki: P. Joshi, et al.
Almmustuhtton: (2013)

Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme
Dahkki: Zou, Kun, et al.
Almmustuhtton: (2009)

Aβ42-to-Aβ40- and Angiotensin-converting Activities in Different Domains of Angiotensin-converting Enzyme
Dahkki: Kun Zou, et al.
Almmustuhtton: (2009)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
Dahkki: Fan, Yujuan, et al.
Almmustuhtton: (2017)

Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme
Dahkki: Elizabeth A. Eckman, et al.
Almmustuhtton: (2006)

The Serpin-Enzyme Complex Receptor Recognizes Soluble, Nontoxic Amyloid-β Peptide but Not Aggregated, Cytotoxic Amyloid-β Peptide
Dahkki: Kimberly Boland, et al.
Almmustuhtton: (1996)

TDP-43 expression influences amyloid β plaque deposition and tau aggregation
Dahkki: Davis, Stephani A., et al.
Almmustuhtton: (2017)

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation
Dahkki: Stephani A. Davis, et al.
Almmustuhtton: (2017)

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β
Dahkki: Korshavn, Kyle J., et al.
Almmustuhtton: (2017)

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β
Dahkki: Kyle J. Korshavn, et al.
Almmustuhtton: (2017)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
Dahkki: Garai, Kanchan, et al.
Almmustuhtton: (2014)

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
Dahkki: Kanchan Garai, et al.
Almmustuhtton: (2014)

Conversion of Aβ43 to Aβ40 by the successive action of angiotensin‐converting enzyme 2 and angiotensin‐converting enzyme
Dahkki: Shuyu Liu, et al.
Almmustuhtton: (2014)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
Dahkki: Du, Wen-Jie, et al.
Almmustuhtton: (2015)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
Dahkki: Wenjie Du, et al.
Almmustuhtton: (2015)

Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells
Dahkki: Mikhail Matveyenka, et al.
Almmustuhtton: (2025)

Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
Dahkki: Wang, Qiuming, et al.
Almmustuhtton: (2013)

Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
Dahkki: Qiuming Wang, et al.
Almmustuhtton: (2013)

Amyloid β-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
Dahkki: Hemming, Matthew L., et al.
Almmustuhtton: (2005)

Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme
Dahkki: Larmuth, Kate M., et al.
Almmustuhtton: (2016)

Amyloid β-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
Dahkki: Matthew L. Hemming, et al.
Almmustuhtton: (2005)

A New Motif in the N‐Terminal of Acetylcholinesterase Triggers Amyloid‐β Aggregation and Deposition
Dahkki: Hou, Li‐Na, et al.
Almmustuhtton: (2013)

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
Dahkki: Jin, Sha, et al.
Almmustuhtton: (2016)

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
Dahkki: Sha Jin, et al.
Almmustuhtton: (2016)

β‐Amyloid aggregation and heterogeneous nucleation
Dahkki: Srivastava, Atul K., et al.
Almmustuhtton: (2019)

β‐Amyloid aggregation and heterogeneous nucleation
Dahkki: Atul Srivastava, et al.
Almmustuhtton: (2019)

Aggregation and structure of amyloid β-protein
Dahkki: Kenjiro Ono, et al.
Almmustuhtton: (2021)

Inhibition of Amyloid β Protein Aggregation and Neurotoxicity by Rifampicin
Dahkki: Takami Tomiyama, et al.
Almmustuhtton: (1996)

Heparin Nanoparticles for β Amyloid Binding and Mitigation of β Amyloid Associated Cytotoxicity
Dahkki: Wang, Peng, et al.
Almmustuhtton: (2014)

Angiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology
Dahkki: Kehoe, Patrick Gavin, et al.
Almmustuhtton: (2016)