Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells.
W e report that osteopontin (OPN), a secreted, kg-Gly-Asp-containing phosphoprotein expressed at high levels in the kidney, suppresses nitric oxide (NO) synthesis induced by the inflammatory mediators y-interferon and lipopolysaccharide in primary mouse kidney proximal tubule epithelial cells.Northe...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1994
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| Online Access: | https://doi.org/10.1016/s0021-9258(17)42407-0 |
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