Site-specific DNA damage induced by hydrazine in the presence of manganese and copper ions. The role of hydroxyl radical and hydrogen atom
The mechanism of DNA damage by hydrazine in the presence of metal ions was investigated by DNA sequencing technique and ESR-spin trapping method. Hydrazine caused DNA damage in the presence of Mn(III), Mn(II), Cu(II), Co(II), and Fe(III). The order of inducing effect on hydrazine-dependent DNA damag...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
1991
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| 在線閱讀: | https://doi.org/10.1016/s0021-9258(18)52324-3 |
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