Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis

Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis

Nonalcoholic fatty liver disease (NAFLD) is associated with the development of metabolic syndromes and hepatocellular carcinoma (HCC). Cholesterol accumulation is related to NAFLD, whereas its detailed mechanism is not fully understood. Previously, we reported that glycine N-methyltransferase (GNMT)...

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Hlavní autoři: Yi‐Jen Liao, Tzu-Lang Chen, Tzong‐Shyuan Lee, Hsiang-An Wang, Chung-Kwe Wang, Li-Ying Liao, Ru‐Shi Liu, Shiu‐Feng Huang, Yi‐Ming Arthur Chen
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.2119/molmed.2011.00258
https://molmed.biomedcentral.com/counter/pdf/10.2119/molmed.2011.00258
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https://doi.org/10.2119/molmed.2011.00258
https://molmed.biomedcentral.com/counter/pdf/10.2119/molmed.2011.00258

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