α-Fetoprotein Impairs APC Function and Induces Their Apoptosis

Abstract α-Fetoprotein (AFP) is a tumor-associated Ag, and its serum level is elevated in patients with hepatocellular carcinoma (HCC). In vitro, AFP induces functional impairment of dendritic cells (DCs). This was demonstrated by the down-regulation of CD40 and CD86 molecules and the impairment of...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Soon Ho Um, Catherine Mulhall, Akeel Alisa, Annette Ives, John Karani, Roger Williams, Antonio Bertoletti, Shahriar Behboudi
Формат: Artigo
Хэл сонгох:англи
Хэвлэсэн: 2004
Онлайн хандалт:https://doi.org/10.4049/jimmunol.173.3.1772
https://journals.aai.org/jimmunol/article-pdf/173/3/1772/1185903/1772.pdf
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