α-Fetoprotein Impairs APC Function and Induces Their Apoptosis
Abstract α-Fetoprotein (AFP) is a tumor-associated Ag, and its serum level is elevated in patients with hepatocellular carcinoma (HCC). In vitro, AFP induces functional impairment of dendritic cells (DCs). This was demonstrated by the down-regulation of CD40 and CD86 molecules and the impairment of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2004
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| Online Access: | https://doi.org/10.4049/jimmunol.173.3.1772 https://journals.aai.org/jimmunol/article-pdf/173/3/1772/1185903/1772.pdf |
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