<i>EZH2</i> and <i>KDM6A</i> Act as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification
The methyltransferase, Enhancer of Zeste homology 2 (EZH2), trimethylates histone 3 lysine 27 (H3K27me3) on chromatin and this repressive mark is removed by lysine demethylase 6A (KDM6A). Loss of these epigenetic modifiers results in developmental defects. We demonstrate that Ezh2 and Kdm6a transcri...
Shranjeno v:
| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | angleščina |
| Izdano: |
2013
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| Online dostop: | https://doi.org/10.1002/stem.1573 https://academic.oup.com/stmcls/article-pdf/32/3/802/41983793/stmcls_32_3_802.pdf |
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