Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3

The activity of the NF-kappa B transcription factor is controlled through cytoplasmic retention by either of two types of molecules: the inhibitor I kappa B alpha/MAD3 or the p105 and p100 precursors of the p50 and p52 DNA-binding subunits. Treatment of cells with classical NF-kappa B inducers such...

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Bibliographic Details
Main Authors: Eduardo Muñóz, Gilles Courtois, Philippe Veschambre, Pierre Jalinot, Alain Israël
Format: Artigo
Language:English
Published: 1994
Online Access:https://doi.org/10.1128/jvi.68.12.8035-8044.1994
https://jvi.asm.org/content/jvi/68/12/8035.full.pdf
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