Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3
The activity of the NF-kappa B transcription factor is controlled through cytoplasmic retention by either of two types of molecules: the inhibitor I kappa B alpha/MAD3 or the p105 and p100 precursors of the p50 and p52 DNA-binding subunits. Treatment of cells with classical NF-kappa B inducers such...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Englisch |
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1994
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Online-Zugang: | https://doi.org/10.1128/jvi.68.12.8035-8044.1994 https://jvi.asm.org/content/jvi/68/12/8035.full.pdf |
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