Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells.
Tumor necrosis factor (TNF) is a monokine that induces pleiotropic events in both transformed and normal cells. These effects are initiated by the binding of TNF to high affinity cell surface receptors. The post-receptor events and signaling mechanisms induced by TNF, however, have remained unknown....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1988
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| Online Access: | https://doi.org/10.1016/s0021-9258(19)81506-5 |
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