Genetically predicted body mass index and Alzheimer's disease–related phenotypes in three large samples: Mendelian randomization analyses

Genetically predicted body mass index and Alzheimer's disease–related phenotypes in three large samples: Mendelian randomization analyses

Abstract Observational research shows that higher body mass index (BMI) increases Alzheimer's disease (AD) risk, but it is unclear whether this association is causal. We applied genetic variants that predict BMI in Mendelian randomization analyses, an approach that is not biased by reverse caus...

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Autores principales: Shubhabrata Mukherjee, Stefan Walter, John Kauwe, Andrew J. Saykin, David A. Bennett, Eric B. Larson, Paul K. Crane, M. Maria Glymour
Formato: Artigo
Lenguaje:inglés
Publicado: 2015
Acceso en línea:https://doi.org/10.1016/j.jalz.2015.05.015
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https://doi.org/10.1016/j.jalz.2015.05.015

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