Resultats de la cerca - Yuan-Ta Lin

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  1. 1
    Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy†

    Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy† per Hsin-Lan Wen, Yuan-Ta Lin, Chen-Hung Ting, Sue Lin‐Chao, Hung Li, Hsiu Mei Hsieh‐Li

    Publicat 2010
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  2. 2
    Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models

    Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models per Yuan-Ta Lin, Yijuang Chern, Che-Kun James Shen, Hsin-Lan Wen, Ya-Chin Chang, Hung Li, Tzu-Hao Cheng, Hsiu Mei Hsieh‐Li

    Publicat 2011
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  3. 3
    Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease

    Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's diseas... per Kuan-Yu Liu, Yu‐Chiau Shyu, Brett A. Barbaro, Yuan-Ta Lin, Yijuang Chern, Leslie M. Thompson, Che-Kun James Shen, J. Lawrence Marsh

    Publicat 2014
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  4. 4
    Defining a Link with Autosomal-Dominant Polycystic Kidney Disease in Mice with Congenitally Low Expression of Pkd1

    Defining a Link with Autosomal-Dominant Polycystic Kidney Disease in Mice with Congenitally Low Expression of Pkd1 per Si‐Tse Jiang, Yuan‐Yow Chiou, Ellian Wang, Hsiu-Kuan Lin, Yuan-Ta Lin, Ying-Chih Chi, Chi-Kuang Leo Wang, Ming‐Jer Tang, Hung Li

    Publicat 2006
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  5. 5
    Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior

    Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior per Alexi Nott, Jemmie Cheng, Fan Gao, Yuan-Ta Lin, Elizabeta Gjoneska, Tak Ko, Paras S. Minhas, Alicia V. Zamudio, Jia Meng, Feiran Zhang, Peng Jin, Li‐Huei Tsai

    Publicat 2016
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  6. 6
    APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation

    APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation per Se-In Lee, Woojin Jeong, Heejin Lim, Sukhee Cho, Hyein Lee, Yonghee Jang, Joonho Cho, Simsung Bae, Yuan-Ta Lin, Li‐Huei Tsai, Dae Won Moon, Jinsoo Seo

    Publicat 2021
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  7. 7
    REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

    REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease per Katharina Meyer, Heather Feldman, Tao Lu, Derek Drake, Elaine T. Lim, King‐Hwa Ling, Nicholas A. Bishop, Ying Pan, Jinsoo Seo, Yuan-Ta Lin, Susan C. Su, George M. Church, Li-Huei Tsai, Bruce A. Yankner

    Publicat 2019
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  8. 8
    Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

    Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes per Joel Blanchard, Michael Bula, José Dávila-Velderrain, Leyla Anne Akay, Lena Zhu, Alexander Frank, Matheus B. Victor, Julia Maeve Bonner, Hansruedi Mathys, Yuan-Ta Lin, Tak Ko, David A. Bennett, Hugh P. Cam, Manolis Kellis, Li‐Huei Tsai

    Publicat 2020
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  9. 9
    PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

    PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4 per Priyanka Narayan, Grzegorz Sienski, Julia Maeve Bonner, Yuan-Ta Lin, Jinsoo Seo, Valeriya Baru, Aftabul Haque, Blerta Milo, Leyla Anne Akay, Agnese Graziosi, Yelena Freyzon, Dirk Landgraf, William R. Hesse, Julie S. Valastyan, M. Inmaculada Barrasa, Li‐Huei Tsai, Susan Lindquist

    Publicat 2020
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  10. 10
    Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models

    Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models per Hong Seok Shim, James W. Horner, Chang‐Jiun Wu, Jiexi Li, Zheng D. Lan, Shan Jiang, Xueping Xu, Wen‐Hao Hsu, Tomasz Żal, Ivonne I. Flores, Pingna Deng, Yuan-Ta Lin, Li‐Huei Tsai, Yanru Wang, Ronald A. DePinho

    Publicat 2021
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  11. 11
    Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia

    Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia per Jinsoo Seo, Oleg Kritskiy, L. Ashley Watson, Scarlett J. Barker, Dilip Dey, Waseem Raja, Yuan-Ta Lin, Tak Ko, Sukhee Cho, Jay Penney, M. Catarina Silva, Steven D. Sheridan, Diane Lucente, James F. Gusella, Bradford C. Dickerson, Stephen J. Haggarty, Li‐Huei Tsai

    Publicat 2017
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  12. 12
    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types per Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather Feldman, Hsin-Lan Wen, Jay Penney, Hugh P. Cam, Elizabeta Gjoneska, Waseem Raja, Jemmie Cheng, Richard Rueda, Oleg Kritskiy, Fatema Abdurrob, Zhuyu Peng, Blerta Milo, Chung Jong Yu, Sara Elmsaouri, Dilip Dey, Tak Ko, Bruce A. Yankner, Li‐Huei Tsai

    Publicat 2018
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  13. 13
    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types per Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather Feldman, Hsin-Lan Wen, Jay Penney, Hugh P. Cam, Elizabeta Gjoneska, Waseem Raja, Jemmie Cheng, Richard Rueda, Oleg Kritskiy, Fatema Abdurrob, Zhuyu Peng, Blerta Milo, Chung Jong Yu, Sara Elmsaouri, Dilip Dey, Tak Ko, Bruce A. Yankner, Li‐Huei Tsai

    Publicat 2018
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  14. 14
    APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

    APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes per Joel Blanchard, Leyla Anne Akay, José Dávila-Velderrain, Djuna von Maydell, Hansruedi Mathys, Shawn M. Davidson, Audrey H. Effenberger, Chih‐Yu Chen, Kristal Maner-Smith, Ihab Hajjar, Eric A. Ortlund, Michael Bula, Emre Agbas, Ayesha P. Ng, Xueqiao Jiang, Martin C. Kahn, Cristina Blanco‐Duque, Nicolas Lavoie, Liwang Liu, Ricardo Reyes‐Chilpa, Yuan-Ta Lin, Tak Ko, Lea R’Bibo, William T. Ralvenius, David A. Bennett, Hugh P. Cam, Manolis Kellis, Li‐Huei Tsai

    Publicat 2022
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  15. 15
    Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy

    Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy per Mari Aikio, Hana M. Odeh, Heike J. Wobst, Bo Lim Lee, Úna Chan, Jocelyn C. Mauna, Korrie L. Mack, Bradley Class, Thomas A. Ollerhead, Alice F. Ford, Edward M. Barbieri, Ryan R. Cupo, Lauren E. Drake, Joshua L. Smalley, Yuan-Ta Lin, Stephanie Lam, Reuben Thomas, Nicholas A. Castello, Ashmita Baral, Jenna N. Beyer, Mohd Altaf Najar, John Dunlop, Aaron D. Gitler, Ashkan Javaherian, Julia Kaye, George M. Burslem, Dean G. Brown, Christopher J. Donnelly, Steven Finkbeiner, Stephen J. Moss, Nicholas J. Brandon, James Shorter

    Publicat 2025
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