Хайлтын үр дүнгүүд - Youyan Zhang

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  1. 1
    <i>Nf1</i> Regulates Hematopoietic Progenitor Cell Growth and Ras Signaling in Response to Multiple Cytokines

    <i>Nf1</i> Regulates Hematopoietic Progenitor Cell Growth and Ras Signaling in Response to Multiple Cytokines -н Youyan Zhang, Terry A. Vik, John Ryder, Edward F. Srour, Tyler Jacks, Kevin Shannon, D. Wade Clapp

    Хэвлэсэн 1998
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    Artigo
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  2. 2
    Nf1 and Gmcsf Interact in Myeloid Leukemogenesis

    Nf1 and Gmcsf Interact in Myeloid Leukemogenesis -н Ron A. Birnbaum, Aengus O’Marcaigh, Z. Wardak, Youyan Zhang, Glenn Dranoff, Tyler Jacks, D. Wade Clapp, Kevin Shannon

    Хэвлэсэн 2000
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    Artigo
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  3. 3
    Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization

    Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization -н Zhiqiang Li, Tiruneh Hailemariam, Hongwen Zhou, Yan Li, Dale C. Duckworth, David A. Peake, Youyan Zhang, Ming‐Shang Kuo, Guoqing Cao, Xian‐Cheng Jiang

    Хэвлэсэн 2007
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    Artigo
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  4. 4
    The CDK4/6 Inhibitor LY2835219 Overcomes Vemurafenib Resistance Resulting from MAPK Reactivation and Cyclin D1 Upregulation

    The CDK4/6 Inhibitor LY2835219 Overcomes Vemurafenib Resistance Resulting from MAPK Reactivation and Cyclin D1 Upregulation -н Vipin Yadav, Teresa F. Burke, Lysiane Huber, Robert D. Van Horn, Youyan Zhang, Sean G. Buchanan, Edward M. Chan, James J. Starling, Richard P. Beckmann, Sheng-Bin Peng

    Хэвлэсэн 2014
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    Artigo
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  5. 5
    Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure

    Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressur... -н Guoqing Cao, Thomas P. Beyer, Youyan Zhang, Robert J. Schmidt, Yan Chen, Sandra L. Cockerham, Karen M. Zimmerman, Sotirios K. Karathanasis, Ellen A. Cannady, Todd Fields, Nathan B. Mantlo

    Хэвлэсэн 2011
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    Artigo
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  6. 6
    KRASG12C-independent feedback activation of wild-type RAS constrains KRASG12C inhibitor efficacy

    KRASG12C-independent feedback activation of wild-type RAS constrains KRASG12C inhibitor efficacy -н Meagan B. Ryan, Oluwadara Coker, Alexey V. Sorokin, Katerina A. Fella, Haley Barnes, Edmond Wong, Preeti Kanikarla Marie, Fengqin Gao, Youyan Zhang, Lian Zhou, Scott Kopetz, Ryan B. Corcoran

    Хэвлэсэн 2022
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    Artigo
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  7. 7
    Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo

    Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo -н Guoqing Cao, Thomas P. Beyer, Xiao Yang, Robert J. Schmidt, Youyan Zhang, William R. Bensch, Raymond F. Kauffman, Hong Gao, Timothy P. Ryan, Liang Yu, Patrick I. Eacho, Xian‐Cheng Jiang

    Хэвлэсэн 2002
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    Artigo
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  8. 8
    LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

    LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer -н Eliza Vakana, Susan E. Pratt, Wayne Blosser, Michele Dowless, Nicholas Simpson, Xiu‐Juan Yuan, Susan Jaken, Jason R. Manro, Jennifer R. Stephens, Youyan Zhang, Lysiane Huber, Sheng-Bin Peng, Louis F. Stancato

    Хэвлэсэн 2016
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    Artigo
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  9. 9
    Oncogenic <i>BRAF</i> Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120

    Oncogenic <i>BRAF</i> Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120 -н Shih-Hsun Chen, Youyan Zhang, Robert D. Van Horn, Tinggui Yin, Sean G. Buchanan, Vipin Yadav, Igor Mochalkin, Swee Seong Wong, Yong Yue, Lysiane Huber, Ilaria Conti, James R. Henry, James J. Starling, Gregory D. Plowman, Sheng-Bin Peng

    Хэвлэсэн 2016
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    Artigo
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  10. 10
    Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets

    Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets -н Ying Chen, Jeremy McGee, Xian‐Ming Chen, Thompson N. Doman, Xueqian Gong, Youyan Zhang, Nicole Hamm, Xiwen Ma, Richard E. Higgs, Shripad V. Bhagwat, Sean G. Buchanan, Sheng-Bin Peng, Kirk A. Staschke, Vipin Yadav, Yong Yue, Hosein Kouros‐Mehr

    Хэвлэсэн 2014
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    Artigo
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  11. 11
    Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis

    Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis -н Yuewei Qian, Robert J. Schmidt, Youyan Zhang, Shaoyou Chu, Aimin Lin, He Wang, Xiliang Wang, Thomas P. Beyer, William R. Bensch, Weiming Li, Mariam Ehsani, Deshun Lu, Robert J. Konrad, Patrick I. Eacho, David E. Moller, Sotirios K. Karathanasis, Guoqing Cao

    Хэвлэсэн 2007
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    Artigo
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  12. 12
    Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity

    Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity -н Zhiqiang Li, Hongqi Zhang, Jing Liu, Chien-Ping Liang, Yan Li, Yue Li, Gladys Teitelman, Thomas P. Beyer, Hai H. Bui, David A. Peake, Youyan Zhang, P E Sanders, Ming‐Shang Kuo, Tae‐Sik Park, Guoqing Cao, Xian‐Cheng Jiang

    Хэвлэсэн 2011
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    Artigo
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  13. 13
    Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with <i>BRAF</i> or <i>KRAS</i> Mutations

    Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with <i>BRAF</i> or <i>KRAS</i> Mutations -н Yung-Mae Yao, Gregory P. Donoho, Philip W. Iversen, Youyan Zhang, Robert D. Van Horn, Amélie Forest, Ruslan D. Novosiadly, Yue Webster, Philip J. Ebert, Steven M. Bray, Jason C. Ting, Amit Aggarwal, James R. Henry, Ramón V. Tiu, Gregory D. Plowman, Sheng‐Bin Peng

    Хэвлэсэн 2017
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    Artigo
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  14. 14
    Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis

    Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis -н Guoqing Cao, Liang Yu, Carol L. Broderick, Brian A. Oldham, Thomas Beyer, Robert J. Schmidt, Youyan Zhang, Keith R. Stayrook, Chen S. Suen, Keith A. Otto, Anne Reifel Miller, Jiannong Dai, Patricia Foxworthy, Hong Gao, Timothy P. Ryan, Xian‐Cheng Jiang, Thomas P. Burris, Patrick I. Eacho, Garret J. Etgen

    Хэвлэсэн 2003
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    Artigo
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  15. 15
    Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

    Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers -н Sheng-Bin Peng, James R. Henry, Michael D. Kaufman, Wei-Ping Lu, Bryan D. Smith, Subha Vogeti, Thomas J. Rutkoski, Scott Wise, Lawrence Chun, Youyan Zhang, Robert D. Van Horn, Tinggui Yin, Xiaoyi Zhang, Vipin Yadav, Shih-Hsun Chen, Xueqian Gong, Xiwen Ma, Yue Webster, Sean G. Buchanan, Igor Mochalkin, Lysiane Huber, Lisa Kays, Gregory P. Donoho, Jennie Walgren, Denis McCann, Phenil J. Patel, Ilaria Conti, Gregory D. Plowman, James J. Starling, Daniel L. Flynn

    Хэвлэсэн 2015
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    Artigo
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  16. 16
    Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-<i>d</i>]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against <i>BRAF</i> or <i>RAS</i> Mutant Tumor Cells

    Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-<i>d</i>]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Pa... -н James R. Henry, Michael D. Kaufman, Sheng-Bin Peng, Yu Mi Ahn, Timothy M. Caldwell, Lakshminarayana Vogeti, Hanumaiah Telikepalli, Wei-Ping Lu, Molly M. Hood, Thomas J. Rutkoski, Bryan D. Smith, Subha Vogeti, David F. Miller, Scott Wise, Lawrence Chun, Xiaoyi Zhang, Youyan Zhang, Lisa Kays, Philip A. Hipskind, A.D. Wrobleski, Karen L. Lobb, Julia M. Clay, Jeffrey Cohen, Jennie Walgren, Denis McCann, Phenil J. Patel, David K. Clawson, Sherry Guo, Danalyn Manglicmot, C. Groshong, Cheyenne Logan, James J. Starling, Daniel L. Flynn

    Хэвлэсэн 2015
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    Artigo
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