Resultats de la cerca - Yasuhiro Funahashi

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  1. 1
    Notch signaling regulates tumor angiogenesis by diverse mechanisms

    Notch signaling regulates tumor angiogenesis by diverse mechanisms per Joseph Dufraine, Yasuhiro Funahashi, Jan Kitajewski

    Publicat 2008
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  2. 2
    Neuronal Polarity: Positive and Negative Feedback Signals

    Neuronal Polarity: Positive and Negative Feedback Signals per Tetsuya Takano, Yasuhiro Funahashi, Kozo Kaibuchi

    Publicat 2019
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  3. 3
    Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy

    Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy per Kenji Ichikawa, Saori Watanabe Miyano, Yukinori Minoshima, Junji Matsui, Yasuhiro Funahashi

    Publicat 2020
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  4. 4
    Extracellular and Intracellular Signaling for Neuronal Polarity

    Extracellular and Intracellular Signaling for Neuronal Polarity per Takashi Namba, Yasuhiro Funahashi, Shinichi Nakamuta, Chundi Xu, Tetsuya Takano, Kozo Kaibuchi

    Publicat 2015
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  5. 5
    Multi-Kinase Inhibitor E7080 Suppresses Lymph Node and Lung Metastases of Human Mammary Breast Tumor MDA-MB-231 via Inhibition of Vascular Endothelial Growth Factor-Receptor (VEGF-R) 2 and VEGF-R3 Kinase

    Multi-Kinase Inhibitor E7080 Suppresses Lymph Node and Lung Metastases of Human Mammary Breast Tumor MDA-MB-231 via Inhibition of Vascular Endothelial Growth Factor-Receptor (VEGF-... per Junji Matsui, Yasuhiro Funahashi, Toshimitsu Uenaka, Tatsuo Watanabe, Akihiko Tsuruoka, Makoto Asada

    Publicat 2008
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  6. 6
    Radial Glial Cell–Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site

    Radial Glial Cell–Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site per Chundi Xu, Yasuhiro Funahashi, Takashi Watanabe, Tetsuya Takano, Shinichi Nakamuta, Takashi Namba, Kozo Kaibuchi

    Publicat 2015
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  7. 7
    Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity

    Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity per Yasuhiro Funahashi, Carrie J. Shawber, Anshula Sharma, Emi Kanamaru, Yun K. Choi, Jan Kitajewski

    Publicat 2011
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  8. 8
    Notch regulates the angiogenic response via induction of VEGFR-1

    Notch regulates the angiogenic response via induction of VEGFR-1 per Yasuhiro Funahashi, Carrie J. Shawber, Marina Vorontchikhina, Anshula Sharma, Hasina H. Outtz, Jan Kitajewski

    Publicat 2010
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  9. 9
    Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models

    Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models per Masahiro Matsuki, Taisuke Hoshi, Yuji Yamamoto, Megumi Ikemori‐Kawada, Yukinori Minoshima, Yasuhiro Funahashi, Junji Matsui

    Publicat 2018
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  10. 10
    E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

    E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis... per Junji Matsui, Yuji Yamamoto, Yasuhiro Funahashi, Akihiko Tsuruoka, Tatsuo Watanabe, Toshiaki WAKABAYASHI, Toshimitsu Uenaka, Makoto Asada

    Publicat 2007
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  11. 11
    Gene Expression Profiling Reveals Epithelial Mesenchymal Transition (EMT) Genes Can Selectively Differentiate Eribulin Sensitive Breast Cancer Cells

    Gene Expression Profiling Reveals Epithelial Mesenchymal Transition (EMT) Genes Can Selectively Differentiate Eribulin Sensitive Breast Cancer Cells per Zoltán Dezső, Judith Oestreicher, Amy Weaver, Stephanie Santiago, Sergei Agoulnik, Jesse C. Chow, Yoshiya Oda, Yasuhiro Funahashi

    Publicat 2014
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  12. 12
    Lenvatinib mesilate (LEN) enhanced antitumor activity of a PD-1 blockade agent by potentiating Th1 immune response

    Lenvatinib mesilate (LEN) enhanced antitumor activity of a PD-1 blockade agent by potentiating Th1 immune response per Yu Kato, Xiaoyi Bao, S. Macgrath, Kimiyo Tabata, Yusaku Hori, Sho Tachino, M. Matijevici, Yasuhiro Funahashi, Junji Matsui

    Publicat 2016
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  13. 13
    Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models

    Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models per Osamu Tohyama, Junji Matsui, Kotaro Kodama, Naoko Hata-Sugi, Takayuki Kimura, Kiyoshi Okamoto, Yukinori Minoshima, Masao Iwata, Yasuhiro Funahashi

    Publicat 2014
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  14. 14
    The LEAP Program: Lenvatinib Plus Pembrolizumab for the Treatment of Advanced Solid Tumors

    The LEAP Program: Lenvatinib Plus Pembrolizumab for the Treatment of Advanced Solid Tumors per Matthew H. Taylor, Emmett V. Schmidt, Corina E. Dutcus, Elaine M. Pinheiro, Yasuhiro Funahashi, Gregory M. Lubiniecki, Drew Rasco

    Publicat 2020
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  15. 15
    Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization

    Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization per Kiyoshi Okamoto, Megumi Ikemori‐Kawada, A. Jestel, Konstanze von König, Yasuhiro Funahashi, Tomohiro Matsushima, Akihiko Tsuruoka, Atsushi Inoue, Junji Matsui

    Publicat 2014
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  16. 16
    Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR–MAPK cascades

    Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR–MAPK cascades per Taisuke Hoshi, Saori Watanabe Miyano, Hideki Watanabe, Regina Mikie Kanada Sonobe, Yuki Seki, Etsuko Ohta, K. Nomoto, Junji Matsui, Yasuhiro Funahashi

    Publicat 2019
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  17. 17
    A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

    A Foxo/Notch pathway controls myogenic differentiation and fiber type specification per Tadahiro Kitamura, Yukari Kitamura, Yasuhiro Funahashi, Carrie J. Shawber, Diego H. Castrillón, Ramya Kollipara, Ronald A. DePinho, Jan Kitajewski, Domenico Accili

    Publicat 2007
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  18. 18
    CRMP‐2 directly binds to cytoplasmic dynein and interferes with its activity

    CRMP‐2 directly binds to cytoplasmic dynein and interferes with its activity per Nariko Arimura, Atsushi Hattori, Toshihide Kimura, Shinichi Nakamuta, Yasuhiro Funahashi, Shinji Hirotsune, Ken’ya Furuta, Takashi Urano, Yoko Y. Toyoshima, Kozo Kaibuchi

    Publicat 2009
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  19. 19
    Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states

    Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition... per Takeshi Yoshida, Yoichi Ozawa, Takayuki Kimura, Yuki Sato, Galina Kuznetsov, Shan Xu, M. Uesugi, Sergei Agoulnik, Noël Taylor, Yasuhiro Funahashi, Junji Matsui

    Publicat 2014
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  20. 20
    Targeting of tumor growth and angiogenesis underlies the enhanced antitumor activity of lenvatinib in combination with everolimus

    Targeting of tumor growth and angiogenesis underlies the enhanced antitumor activity of lenvatinib in combination with everolimus per Masahiro Matsuki, Yusuke Adachi, Yoichi Ozawa, Takayuki Kimura, Taisuke Hoshi, Kiyoshi Okamoto, Osamu Tohyama, Kaoru Mitsuhashi, Atsumi Yamaguchi, Junji Matsui, Yasuhiro Funahashi

    Publicat 2017
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